Computational depth meets biological intuition
From structural biology to machine learning, ProtoVela combines complementary disciplines — rational protein design over directed evolution — to solve real protein engineering challenges faster, smarter, and entirely in silico.
Structure-based protein design
Rational design grounded in 3D structural data — engineering proteins with precise function, stability and manufacturability in mind.
Sequence engineering
Computational sequence engineering with targeted mutation strategies for better expression, solubility and shelf life.
Machine learning models
Modern ML and AI architectures trained on protein datasets — for property prediction and de novo variant design.
Bioinformatic pipelines
Custom workflows from sequence analysis to structural simulation — built to integrate with your stack.
Stability & expression
Improve thermal and storage stability and enhance recombinant expression in your host system.
Predictive modeling
Simulate molecular behaviour before any wet-lab investment — saving time, budget and resources.
Wet-lab-ready outputs
All designs are documented and prioritized to translate seamlessly into experimental validation.
Confidential collaboration
We treat your IP and data with the highest standards of scientific and contractual care.
De novo miniprotein therapeutics
Hyperstable miniproteins as a compact alternative to monoclonal antibodies — engineered for stability, manufacturability and tissue penetration.
Antimicrobial peptides (AMPs)
Computational design of antimicrobial peptides — focused on overcoming bacterial efflux pumps and on clean resistance profiles.
Explore further
Five entry points into ProtoVela — from process and proof to the intro call.
Expertise
Services, molecule classes and scientific application areas in detail.
Why ProtoVela
Principles, optimisation targets and the eight-step design process.
About
Team, location and scientific leadership behind ProtoVela.
Blog
Field notes on AI, structural biology and protein design.
Contact
Book a free intro call and Project Assessment.
